by Nicholas Mitsakos | Artificial Intelligence, Biotechnology, Book Chapter, Finance, Financial Technology, Investment Principles, Technology, The Market, Writing and Podcasts
The onslaught of market-making bad news seems almost a daily event. A gloomy picture of slowing economic growth, elevated inflation, and confusing fiscal and monetary policy has added a lethal mixture to the market’s performance. Fiscal stimulus is sidelined, and monetary policy is constricting economic growth and entrepreneurial innovation. It makes for a gloomy outlook and an even more depressing long-term perspective. The next 10 years look more like a lost decade. High-growth company valuations have been significantly discounted, and over time as discount rates drop, their valuations are likely to increase substantially. Higher-yielding fixed income securities will be a standout performer as interest rates are reduced, the higher-yielding BDCs, REITs, leveraged loan securities, and high cash flow instruments, along with high-dividend equities, will prove extremely attractive and are currently available at bargain prices. Providers of value and users of value will be the winners for the next decade. Those generating real cash flow and disruptive innovation will define the next decade.
by Nicholas Mitsakos | Artificial Intelligence, Biotechnology, Book Chapter, Technology, Transformative businesses, Writing and Podcasts
Innovation is unpredictable and astonishing – it can address the world’s most critical issues today, from hunger to efficient energy, to devastating diseases. It is also too often misguided, inefficient, and meaningless – creating nothing more than distractions and wastes of time cloaked in an image of technological wonder. Misguided and manipulative business plans sit side-by-side with the groundbreaking disruptions that may address society’s greatest problems.
by Nicholas Mitsakos | Book Chapter, Digital Assets, Investments, irrationality, Transformative businesses, Writing and Podcasts
It has taken over 30 years for the overnight sensation of the Metaverse, but now hype, money, and large technology companies are charging in. Most obvious and conspicuous is Facebook’s maneuver to change its name to Meta Platforms and commit $10 billion. Microsoft is making a $70 billion acquisition of Activision to mostly focus on Metaverse platform development. Following on top of these two elephants is tens of billions of dollars of venture capital. The opportunity is considered comparable to the original iPhone. None of the iPhone’s component services – mobile phone, computer, camera, and operating system, were new or distinct. The iPhone revolution is the convergence into a single device (or platform) and, most importantly, the entrepreneurial spark that lit millions of application developers to create value from the iPhone platform.
The Metaverse can best be thought of as the intersection of technologies and users. It combines virtual and augmented worlds, virtual assets, digital assets, and gaming into a single platform. However, there doesn’t seem to be anything too disruptive about the Metaverse or Web 3.0. It’s reasonable to be skeptical, and while there is an economic opportunity within the specific creation of Metaverse assets, the real opportunity remains with the infrastructure, intermediaries, picks, shovels, and “the arms dealers” of global digital war.
by Nicholas Mitsakos | Artificial Intelligence, Biotechnology, Book Chapter, Digital Assets, irrationality, Transformative businesses, Writing and Podcasts
Transformation, or euphemistically, “disruption,” creates great opportunities to capture newly created wealth. But, as industries are transforming and strategic disruption is occurring, quite a lot of absurdity and certainly enough terror are associated with some of these extraordinary opportunities to require much greater analysis and understanding.
There are extraordinary risks associated with anything disruptive and transformational. The first disruptor isn’t always the one who creates the most value or is even a sustainable competitive entity.
Innovation does not mean competitive sustainability. Digital platforms, ranging from the internet to digital assets and cryptocurrency are transforming industries globally. But, along with that comes a lot of hyperbole and typically that is followed by very little substance. Great companies use technological disruption, innovation, and transformation to establish themselves and thrive. But they rarely last. Every company, even the most valuable companies such as Apple, Apple, Amazon, Facebook, Netflix, etc. must dynamically transform to stay competitive and valuable.
Transformations are certain. New entities will become very valuable, legacy companies will diminish, and a handful will transform and thrive.
Transformation and sustainability create and capture great wealth, but are far more challenging to identify, and even more challenging to sustain.
by Nicholas Mitsakos | Book Chapter, Investment Principles, Investments, irrationality, The Market, Writing and Podcasts
The world may appear to be a rational, deductive place if you are a scientist. But not if you are an investor attempting to understand how markets work. Financial markets are human creations, and humans are irrational. Economics, a truly dismal social science, is an attempt to look backward and create explanatory algorithms about what happened and why. They may have some success with this. But as predictive models, they are mostly useless. More often, they destroy value versus conveying any understanding about economic and business functions, and therefore, give not only useless but awful and typically value-destroying predictions. Participating in the markets requires a broader, more methodical and disciplined approach. Since irrationality pervades most activity, markets move dramatically with uncertainty, and investors react with dramatic moves based on even more uncertainty and lack a reasonable level of understanding and longer-term perspective about what is going on. The world now is more dynamic, volatile, uncertain, and unpredictable. Irrationality drives most market decisions and rising above the noise to be more thoughtful, think deeply and slowly to understand what’s going on, and identify the handful of factors (typically very few) that make all the difference to investment success is the true challenge we face today. That challenge takes work and thoughtful strategies in our irrational world. That world will remain fundamentally irrational from now on, and thoughtful strategies are the only way to succeed in this irrational environment.
by Nicholas Mitsakos | Book Chapter, Currency, Digital Assets, Investments, Technology, Writing and Podcasts
Super lofty ideas get attention and publicity, but they are not real. Narrow, specific applications are where true foundational value is created. The financial revolution will certainly not be based on a process where someone buys coins or tokens and simply waits for them to increase in value. On top of that, despite the belief that there will be frictionless peer-to-peer transactions, purchasing any cryptocurrency requires a crypto exchange like Coinbase or FTX that charge high trading fees and have questionable security. Blockchain is an evolution for businesses, it is not a disruption or a new infrastructure. It will improve user experiences, regulatory clarity, and interoperability. Crypto proved that digital transfers and settlements were possible, it is the blockchain platform that enables this efficiently and securely. It may be boring and we’re not going to have any stadiums or arenas named after a technology platform, but real change will be driven by a blockchain. The rest is a noisy sideshow.
by Nicholas Mitsakos | Book Chapter, Investment Principles, Investments, The Market, Writing and Podcasts
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by Nicholas Mitsakos | Book Chapter, Investment Principles, Investments, Writing and Podcasts
Investment models that account for uncertainty, volatility, and failure succeed in the long term. Events in Ukraine, oil and natural gas markets, commodities, supply chain disruption, and spiking inflation highlight that, while none of these were predictable, all represent increasing uncertainty permeating all markets. The pandemic and war in Ukraine were unforeseen, but that’s just the point, unforeseen events will occur. It is a waste of time to try to predict the specifics, it is an essential investment strategy to manage risk to not only withstand but profit from “certain uncertainty.” Irrationality, not only in human behavior (with unfortunate, often tragic results) but market movements, investment volatility, and bewildering prices, is another certainty. “Mr. Market” as Benjamin Graham said, “is an irrational schizophrenic.” Investing as if he is not assures an investment strategy that will ultimately fail. An increasing number of growth and momentum investment funds are shutting down after sustaining significant losses recently, a sign of the severe pain the selloff in growth stocks is inflicting. More importantly, it signals an inability for investment funds to manage risk and understand that markets and investments do not move in a singular direction for long, and the correction is sudden and painful – regardless of how compelling “momentum” may seem. Risk management is the key to investment sustainability, but this seems to go ignored among most investment professionals. Frequent and extreme volatility is here to stay, and that is likely to decimate growth and momentum funds, as well as highly leveraged equity investment funds (from LTCM in 1998 to Archegos in 2021, the lesson is never learned for long – and there will be more examples to come). Clear and coherent markets, free from political agenda, bad compromises, and ineffective regulation are almost nonexistent. The consequences continue to be pyrotechnic.
by Nicholas Mitsakos | Biotechnology, Book Chapter, Health Care, Transformative businesses, Writing and Podcasts
While messenger RNA (mRNA) has been catching recent headlines thanks to its ability to fight Covid, the combination of a global pandemic and the miraculous mRNA vaccine development in less than one year (when typical timelines approach 10 years) has made mRNA life science’s overnight sensation even though the underlying scientific knowledge is based on discoveries from over 20 years ago. Still, mRNA has the promise to disrupt life sciences and drug development and create enormous economic value.
There are fantastic fortunes to be made in mRNA technology. Moderna and BioNTech have created over $100 billion of value collectively, as of February 2022. That kind of value creation will not be ignored by a combination of firms within an industry with hundreds of billions to invest. There will be an incredible future of development, capital availability, and industry focus until all potential options are exhausted. But, mRNA has a fantastic future, even if it ultimately lives only in labs and R&D centers spread around the globe. It will become an area of focus for every major pharmaceutical company and most biotechs in some form from now on.
by Nicholas Mitsakos | Artificial Intelligence, Biotechnology, Book Chapter, Technology, Writing and Podcasts
Artificial intelligence, while generating powerful tools for analysis, is only the beginning of a more ambitious phase making AI systems more accurate, less biased, and effective prediction tools. Gathering more and more raw data does not create value. One cannot simply push a button and have valuable output generated. Data needs to be collected, processed, stored, managed, analyzed, and visualized – only then can we begin to interpret the results. Each step is challenging, and every step in this cycle requires massive amounts of work and value-added tools. It’s not just the software and hardware artifacts we produce that will be physically present everywhere and touch our lives all the time, it will be the computational concepts we use to approach and solve problems, manage our daily lives, and communicate and interact with other people. It will be a reality when it is so integral to our lives it disappears. The problems and solutions we address are limited only by our own curiosity and creativity.
by Nicholas Mitsakos | Book Chapter, Digital Assets, Investment Principles, Technology, Transformative businesses, Writing and Podcasts
Every industry consolidates to a handful of centralized competitors. That will never change regardless of current dreams of decentralization from Web 3.0. Modern computing is a constant struggle between decentralization and centralization. Centralization wins eventually, and it will again. These dynamics, combined with the latest crash that may cool investors’ appetite for all things crypto, suggest that Web 3.0 will not dislodge Web 2.0. Instead, the future may belong to a mix of the two, with Web 3.0 occupying certain niches. Whether or not people keep splurging on NFTs, such tokens make a lot of sense in the metaverse, where they could be used to track ownership of digital objects and move them from one virtual world to another. Web 3.0 may also play a role in the creator economy, assuring intellectual property ownership. NFTs make it easier for creators of online content to make money. In this limited way, at least, even the masters of Web 2.0 see the writing on the wall: on January 20th both Meta and Twitter integrated NFTs into their platforms.
by Nicholas Mitsakos | Book Chapter, Investment Principles, Writing and Podcasts
My new book, “Investment Principles: Strategies for an Irrational World” (Amazon link: Investment Principles: Strategies for an Irrational World.) looks at what’s really required for successful investing. While most authors try to give quick and effortless tips, I believe that a disciplined and methodical approach to investing is essential for true success. This means analytical work and an understanding that goes far beyond a simple summary description.
Successful investing requires understanding global economics, competitive, corporate, and micro-level analysis, game theory, and human emotions and behavior. That’s a lot to understand all at once but can be approached by segmenting each of these complex topics, giving sufficient depth to understand what is fundamentally going on in each area, and then, most valuably, show how these areas interact, enabling much more effective investment decision making.
The goal is to share an informed and distinctive way to think, predict the future with that combined information, and then make choices. Investment success combines predicting the future, the confidence to make bold choices, and the fortitude to stay with those choices.
