by Nicholas Mitsakos | AI Agents, Artificial Intelligence, Biotechnology, Book Chapter, crispr, drug discovery, Health Care, Transformative businesses, Writing and Podcasts
AI cures disease only if the cures already are within a set we have measured, waiting for a better approach. One problem: they do not. Most of human biology has never been observed with detail and understanding sufficient to target a therapy. No amount of inference recovers data that was never collected. The need for AI in life sciences and drug discovery is indisputable. Of roughly ten thousand known human diseases, the large majority have no approved therapy at all; among rare diseases, the figure approaches ninety-five percent. Most approved drugs slow a disease rather than stop it. For the bulk of human illness, medicine offers management or nothing. Humans are systems, and the hardest diseases are within human systems and unsolved. The constraint is not intelligence. It is understanding the system.
by Nicholas Mitsakos | Artificial Intelligence, Biotechnology, Book Chapter, crispr, drug discovery, Health Care, Innovation, Science, Writing and Podcasts
The first gene-edited approved drug (treating sickle cell anemia) is the first commercial rewriting of human genomes. Is this a new “Golden Age” for medicine? There is great promise, and the potential to treat unmet medical needs, scale dramatic innovations to commercial applications, and transform life sciences is enormous. Since every medicine is an intersection of scientific, technical, and clinical understanding, many new treatments are suddenly arriving because of the convergence of dramatic advancements in science, technical knowledge, and clinical results. Modern medicine is witnessing a transformative era of groundbreaking innovations and technological advancements. We are witnessing a renaissance in drug treatment driven by innovations in immunotherapy, weight management, vaccine development, gene editing, and AI. These advances reshape medical treatments and fundamentally alter our approach to health and disease. As these technologies mature and their applications broaden, the future of medicine holds unprecedented potential for improving human health and longevity. A golden age – with a bit of hype.