by Nicholas Mitsakos | Book Chapter, Investment Principles, Investments, Writing and Podcasts
Investment models that account for uncertainty, volatility, and failure succeed in the long term. Events in Ukraine, oil and natural gas markets, commodities, supply chain disruption, and spiking inflation highlight that, while none of these were predictable, all represent increasing uncertainty permeating all markets. The pandemic and war in Ukraine were unforeseen, but that’s just the point, unforeseen events will occur. It is a waste of time to try to predict the specifics, it is an essential investment strategy to manage risk to not only withstand but profit from “certain uncertainty.” Irrationality, not only in human behavior (with unfortunate, often tragic results) but market movements, investment volatility, and bewildering prices, is another certainty. “Mr. Market” as Benjamin Graham said, “is an irrational schizophrenic.” Investing as if he is not assures an investment strategy that will ultimately fail. An increasing number of growth and momentum investment funds are shutting down after sustaining significant losses recently, a sign of the severe pain the selloff in growth stocks is inflicting. More importantly, it signals an inability for investment funds to manage risk and understand that markets and investments do not move in a singular direction for long, and the correction is sudden and painful – regardless of how compelling “momentum” may seem. Risk management is the key to investment sustainability, but this seems to go ignored among most investment professionals. Frequent and extreme volatility is here to stay, and that is likely to decimate growth and momentum funds, as well as highly leveraged equity investment funds (from LTCM in 1998 to Archegos in 2021, the lesson is never learned for long – and there will be more examples to come). Clear and coherent markets, free from political agenda, bad compromises, and ineffective regulation are almost nonexistent. The consequences continue to be pyrotechnic.
by Nicholas Mitsakos | Biotechnology, Book Chapter, Health Care, Transformative businesses, Writing and Podcasts
While messenger RNA (mRNA) has been catching recent headlines thanks to its ability to fight Covid, the combination of a global pandemic and the miraculous mRNA vaccine development in less than one year (when typical timelines approach 10 years) has made mRNA life science’s overnight sensation even though the underlying scientific knowledge is based on discoveries from over 20 years ago. Still, mRNA has the promise to disrupt life sciences and drug development and create enormous economic value.
There are fantastic fortunes to be made in mRNA technology. Moderna and BioNTech have created over $100 billion of value collectively, as of February 2022. That kind of value creation will not be ignored by a combination of firms within an industry with hundreds of billions to invest. There will be an incredible future of development, capital availability, and industry focus until all potential options are exhausted. But, mRNA has a fantastic future, even if it ultimately lives only in labs and R&D centers spread around the globe. It will become an area of focus for every major pharmaceutical company and most biotechs in some form from now on.
by Nicholas Mitsakos | Artificial Intelligence, Biotechnology, Book Chapter, Technology, Writing and Podcasts
Artificial intelligence, while generating powerful tools for analysis, is only the beginning of a more ambitious phase making AI systems more accurate, less biased, and effective prediction tools. Gathering more and more raw data does not create value. One cannot simply push a button and have valuable output generated. Data needs to be collected, processed, stored, managed, analyzed, and visualized – only then can we begin to interpret the results. Each step is challenging, and every step in this cycle requires massive amounts of work and value-added tools. It’s not just the software and hardware artifacts we produce that will be physically present everywhere and touch our lives all the time, it will be the computational concepts we use to approach and solve problems, manage our daily lives, and communicate and interact with other people. It will be a reality when it is so integral to our lives it disappears. The problems and solutions we address are limited only by our own curiosity and creativity.
by Nicholas Mitsakos | Book Chapter, Digital Assets, Investment Principles, Technology, Transformative businesses, Writing and Podcasts
Every industry consolidates to a handful of centralized competitors. That will never change regardless of current dreams of decentralization from Web 3.0. Modern computing is a constant struggle between decentralization and centralization. Centralization wins eventually, and it will again. These dynamics, combined with the latest crash that may cool investors’ appetite for all things crypto, suggest that Web 3.0 will not dislodge Web 2.0. Instead, the future may belong to a mix of the two, with Web 3.0 occupying certain niches. Whether or not people keep splurging on NFTs, such tokens make a lot of sense in the metaverse, where they could be used to track ownership of digital objects and move them from one virtual world to another. Web 3.0 may also play a role in the creator economy, assuring intellectual property ownership. NFTs make it easier for creators of online content to make money. In this limited way, at least, even the masters of Web 2.0 see the writing on the wall: on January 20th both Meta and Twitter integrated NFTs into their platforms.
by Nicholas Mitsakos | Book Chapter, Investment Principles, Writing and Podcasts
My new book, “Investment Principles: Strategies for an Irrational World” (Amazon link: Investment Principles: Strategies for an Irrational World.) looks at what’s really required for successful investing. While most authors try to give quick and effortless tips, I believe that a disciplined and methodical approach to investing is essential for true success. This means analytical work and an understanding that goes far beyond a simple summary description.
Successful investing requires understanding global economics, competitive, corporate, and micro-level analysis, game theory, and human emotions and behavior. That’s a lot to understand all at once but can be approached by segmenting each of these complex topics, giving sufficient depth to understand what is fundamentally going on in each area, and then, most valuably, show how these areas interact, enabling much more effective investment decision making.
The goal is to share an informed and distinctive way to think, predict the future with that combined information, and then make choices. Investment success combines predicting the future, the confidence to make bold choices, and the fortitude to stay with those choices.
by Nicholas Mitsakos | Book Chapter, Panel Discussion, Podcast, Technology, Transformative businesses, Writing and Podcasts
Digital assets are disrupting finance – the world’s largest industry. All assets, intellectual property, and even currency can now be digitized, and anyone can access anything from anywhere. The finance industry is being this intermediated and globalized, economic development and policy will be forever changed.
by Nicholas Mitsakos | Book Chapter, Currency, Economy, Finance, Investment Principles, The Market, Writing and Podcasts
Financial markets are imbalanced and lack liquidity in crucial sectors, even historically stable and predictable markets such as the global bond and currency markets. Investments are slanted in one direction more frequently and the markets are vulnerable to big price swings as a result. These large global markets are not immune to ever more lopsided trades creating extreme volatility. This occurs even when a small change occurs in positions, sentiment, or news. Even the world’s most liquid markets, US dollar currency trades and US Treasuries, are seeing skewed positioning resulting in surprisingly large shifts in prices and Treasury bond yields. The market now leans too far one way or the other, and that imbalance will be forced to reverse more powerfully and unpredictably.
by Nicholas Mitsakos | Book Chapter, Investments, Technology, The Market, Transformative businesses, Writing and Podcasts
Transformation, Valuation, Employment, and Deflation
Disruption to some of the world’s most important industries, deflationary pressure caused by scaling lower-cost businesses, and sustained low interest rates challenge traditional valuation models. Technological platforms, from blockchain-based businesses to energy storage to DNA sequencing, enable unprecedented disruption to business and economic models.
Interest rates will remain low, equity values will remain high, innovation will drive deflationary pressure, and volatility will be intense and frequent. A new approach is required to understand dynamic global competition and sustainable value.
by Nicholas Mitsakos | Book Chapter, Economy, Public Policy, The Market, Writing and Podcasts
A National Investment Authority, an idea gaining traction among the administration, would be responsible for “devising, financing, and executing a long-term national strategy of economic development and reconstruction.”
This is not the job of a government; this is the role of the free market. The market does this quite well, and government does this quite poorly. An NIA is another way to bring misery and inefficiency.
Policy reflective of central planning, socialism, or industrial policy brings misery to all. This discredited philosophy that tortured so many in Eastern Europe and Soviet Russia seems to be getting more traction today bewilderingly. It leads to nothing more than bureaucratic idiocy, waste, and disregard for any consumer needs.
by Nicholas Mitsakos | Book Chapter, Currency, Economy, Public Policy, Writing and Podcasts
Central bank independence and fiscal responsibility matter, even though the Western world is acting as if these rules no longer apply. Well, perhaps. But the world has given us three examples where the consequences are extreme when these basic foundations of economic policy are ignored or violated. Ultimately, if markets lose confidence in a central bank’s independence and thoughtfulness (yes, thinking really matters), or a sovereign government’s fiscal responsibility (where thoughtfulness is never taken for granted), inflation expectations will undermine an economy and make recovery almost hopeless.
by Nicholas Mitsakos | Book Chapter, Investment Principles, Writing and Podcasts
Failures are essential for success. The NASA flight director, Gene Kranz, who is famous for the Apollo 13 quote, “Failure is not an option” has been misunderstood. Mr. Kranz did not mean “don’t fail.” He meant was that there will be a solution, think boldly and courageously because, while the solution may not be obvious to you now, you will find it eventually.
Accepting failures is not accepting failure.
Failures – trial and error, unforeseen roadblocks, creative thinking, visions, and revisions that a minute will reverse – lead to insight, innovation, creativity, and unforeseen breakthroughs. That’s success.
Failure is when you stop.
by Nicholas Mitsakos | Book Chapter, Currency, Digital Assets, Investments, Technology, Writing and Podcasts
Decentralized finance (DeFi) can disrupt global finance – but only if Defi systems and central governments cooperate. Yes, sworn enemies cooperating for the greater good.
While each seems to be the sworn enemy of the other, ultimately, a cooperative relationship between decentralized and efficient (versus anachronistic and cumbersome) financial infrastructure and government central banks with stable currencies is absolutely necessary.
Defi transactions, to scale globally, require stable and predictable value. Government-issued currencies are the only reliable and foreseeable foundation. Cryptocurrencies, such as Bitcoin were never currencies. They are a sideshow that will remain a speculative asset, and increasingly unimportant.
Cryptocurrencies represent an architectural shift in how financial infrastructure and technology interact, and therefore, it is disrupting how the financial industry works globally. It is neither a new kind of money system nor a danger to economic stability. It is more important than that.
